NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity

Autores:
Daniel S. Rincón
Lizdany Flórez-Álvarez
Natalia A. Taborda
Juan C. Hernandez
María T. Rugeles
Wildeman Zapata-Builes
Tipo de recurso:
Article of journal
Fecha de publicación:
2023
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
eng
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/57155
Acceso en línea:
https://hdl.handle.net/20.500.12494/57155
Palabra clave:
HSH
HESN
HIV-1
NK cells
effector capacity
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/4.0/
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repository_id_str
dc.title.none.fl_str_mv NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity
title NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity
spellingShingle NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity
HSH
HESN
HIV-1
NK cells
effector capacity
title_short NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity
title_full NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity
title_fullStr NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity
title_full_unstemmed NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity
title_sort NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacity
dc.creator.fl_str_mv Daniel S. Rincón
Lizdany Flórez-Álvarez
Natalia A. Taborda
Juan C. Hernandez
María T. Rugeles
Wildeman Zapata-Builes
dc.contributor.author.none.fl_str_mv Daniel S. Rincón
Lizdany Flórez-Álvarez
Natalia A. Taborda
Juan C. Hernandez
María T. Rugeles
Wildeman Zapata-Builes
dc.contributor.corporatename.none.fl_str_mv Universidad Cooperativa de Colombia
Universidad de Antioquia
dc.contributor.researchgroup.none.fl_str_mv INFETTARE
dc.subject.proposal.none.fl_str_mv HSH
HESN
HIV-1
NK cells
effector capacity
topic HSH
HESN
HIV-1
NK cells
effector capacity
publishDate 2023
dc.date.issued.none.fl_str_mv 2023-10-05
dc.date.accessioned.none.fl_str_mv 2024-09-27T19:27:28Z
dc.date.available.none.fl_str_mv 2024-09-27T19:27:28Z
dc.type.none.fl_str_mv Artículo de revista
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dc.identifier.citation.none.fl_str_mv Rincón, D.S., Flórez-Álvarez, L., Taborda, N.A. et al. NK cells from Men Who Have Sex with Men at high risk for HIV-1 infection exhibit higher effector capacity. Sci Rep 13, 16766 (2023). https://doi.org/10.1038/s41598-023-44054-1
dc.identifier.issn.none.fl_str_mv 2045-2322
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/57155
dc.identifier.doi.none.fl_str_mv 10.1038/s41598-023-44054-1
dc.identifier.eissn.none.fl_str_mv 2045-2322
identifier_str_mv Rincón, D.S., Flórez-Álvarez, L., Taborda, N.A. et al. NK cells from Men Who Have Sex with Men at high risk for HIV-1 infection exhibit higher effector capacity. Sci Rep 13, 16766 (2023). https://doi.org/10.1038/s41598-023-44054-1
2045-2322
10.1038/s41598-023-44054-1
url https://hdl.handle.net/20.500.12494/57155
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.citationendpage.none.fl_str_mv 13
dc.relation.citationissue.none.fl_str_mv 16766
dc.relation.citationstartpage.none.fl_str_mv 1
dc.relation.citationvolume.none.fl_str_mv 13
dc.relation.ispartofjournal.none.fl_str_mv Scientific Reports
dc.relation.references.none.fl_str_mv 1. Miyazawa, M. et al. The ‘immunologic advantage’ of HIV-exposed seronegative individuals. AIDS 23, 161–175 (2009).
2. Horton, R. E., McLaren, P. J., Fowke, K., Kimani, J. & Ball, T. B. Cohorts for the study of HIV-1-exposed but uninfected individuals: Benefits and limitations. J. Infect. Dis. 202(Suppl 3), S377-381. https:// doi. org/ 10. 1086/ 655971 (2010).
3. Fenizia, C., Saulle, I., Clerici, M. & Biasin, M. Genetic and epigenetic regulation of natural resistance to HIV-1 infection: New approaches to unveil the HESN secret. Expert Rev. Clin. Immunol. 16, 429–445. https:// doi. org/ 10. 1080/ 17446 66X. 2020. 17328 20 (2020).
4. Fauci, A. S., Mavilio, D. & Kottilil, S. NK cells in HIV infection: Paradigm for protection or targets for ambush. Nat. Rev. Immunol. 5, 835–843. https:// doi. org/ 10. 1038/ nri17 11 (2005).
5. Scott-Algara, D. et al. Cutting edge: Increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug users. J. Immunol. 171, 5663–5667. https:// doi. org/ 10. 4049/ jimmu nol. 171. 11. 5663 (2003).
6. Tomescu, C., Abdulhaqq, S. & Montaner, L. J. Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN). Clin. Exp. Immunol. 164, 158–169. https:// doi. org/ 10. 1111/j. 1365- 2249. 2011. 04379.x (2011).
7. Zhao, N. Q. et al. Natural killer cell phenotype is altered in HIV-exposed seronegative women. PLoS One 15, e0238347. https:// doi. org/ 10. 1371/ journ al. pone. 02383 47 (2020).
8. Montoya, C. J., Velilla, P. A., Chougnet, C., Landay, A. L. & Rugeles, M. T. Increased IFN-gamma production by NK and CD3+/ CD56+ cells in sexually HIV-1-exposed but uninfected individuals. Clin. Immunol. 120, 138–146. https:// doi. org/ 10. 1016/j. clim. 2006. 02. 008 (2006).
9. Florez-Alvarez, L. et al. NK cell activity and CD57(+)/NKG2C(high) phenotype are increased in men who have sex with men at high risk for HIV. Front. Immunol. 11, 537044. https:// doi. org/ 10. 3389/ fimmu. 2020. 537044 (2020).
10. Mikulak, J., Oriolo, F., Zaghi, E., Di Vito, C. & Mavilio, D. Natural killer cells in HIV-1 infection and therapy. AIDS 31, 2317–2330. https:// doi. org/ 10. 1097/ qad. 00000 00000 001645 (2017).
11. Pines, H. A., Karris, M. Y. & Little, S. J. Sexual partner concurrency among partners reported by MSM with recent HIV infection. AIDS Behav. 21, 3026–3034. https:// doi. org/ 10. 1007/ s10461- 017- 1855-x (2017).
12. Tieu, H. V. et al. Concurrent partnerships and HIV risk among men who have sex with men in New York City. Sex Transm. Dis. 41, 200–208. https:// doi. org/ 10. 1097/ OLQ. 00000 00000 000090 (2014).
13. Ossa-Giraldo, A. C. et al. Sexual behaviors and factors associated with condomless sexual practice in colombian men who have sex with men at high risk of HIV transmission. Arch. Sexual Behav. 50, 3175–3190. https:// doi. org/ 10. 1007/ s10508- 020- 01856-y (2021).
14. Galvin, S. R. & Cohen, M. S. The role of sexually transmitted diseases in HIV transmission. Nat. Rev. Microbiol. 2, 33–42. https://doi. org/ 10. 1038/ nrmic ro794 (2004).
15. Tobian, A. A. & Quinn, T. C. Herpes simplex virus type 2 and syphilis infections with HIV: An evolving synergy in transmission and prevention. Curr. Opin. HIV AIDS 4, 294–299. https:// doi. org/ 10. 1097/ COH. 0b013 e3283 2c1881 (2009).
16. Bjorkstrom, N. K., Ljunggren, H. G. & Sandberg, J. K. CD56 negative NK cells: Origin, function, and role in chronic viral disease. Trends Immunol. 31, 401–406. https:// doi. org/ 10. 1016/j. it. 2010. 08. 003 (2010).
17. Goodier, M. R. et al. Rapid NK cell differentiation in a population with near-universal human cytomegalovirus infection is attenuated by NKG2C deletions. Blood 124, 2213–2222. https:// doi. org/ 10. 1182/ blood- 2014- 05- 576124 (2014).
18. Camous, X., Pera, A., Solana, R. & Larbi, A. NK cells in healthy aging and age-associated diseases. J. Biomed. Biotechnol. 2012, 195956. https:// doi. org/ 10. 1155/ 2012/ 195956 (2012).
19. Richard, J., Sindhu, S., Pham, T. N., Belzile, J. P. & Cohen, E. A. HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing. Blood 115, 1354–1363. https:// doi. org/ 10. 1182/ blood- 2009- 08- 237370 (2010).
20. Florez-Alvarez, L., Hernandez, J. C. & Zapata, W. NK cells in HIV-1 infection: From basic science to vaccine strategies. Front. Immunol. 9, 2290. https:// doi. org/ 10. 3389/ fimmu. 2018. 02290 (2018).
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spelling Daniel S. RincónLizdany Flórez-ÁlvarezNatalia A. TabordaJuan C. HernandezMaría T. RugelesWildeman Zapata-BuilesUniversidad Cooperativa de ColombiaUniversidad de AntioquiaINFETTARE2024-09-27T19:27:28Z2024-09-27T19:27:28Z2023-10-05Rincón, D.S., Flórez-Álvarez, L., Taborda, N.A. et al. NK cells from Men Who Have Sex with Men at high risk for HIV-1 infection exhibit higher effector capacity. Sci Rep 13, 16766 (2023). https://doi.org/10.1038/s41598-023-44054-12045-2322https://hdl.handle.net/20.500.12494/5715510.1038/s41598-023-44054-12045-23221-13application/pdfengGrupo Infettare, Facultad de Medicina, Universidad Cooperativa de Colombia, Medellín, Colombia.Externohttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://purl.org/coar/access_right/c_abf2https://www.nature.com/articles/s41598-023-44054-1NK cells from Men Who Have Sex with Men at high risk for HIV‑1 infection exhibit higher effector capacityArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersion1316766113Scientific Reports1. Miyazawa, M. et al. The ‘immunologic advantage’ of HIV-exposed seronegative individuals. AIDS 23, 161–175 (2009).2. Horton, R. E., McLaren, P. J., Fowke, K., Kimani, J. & Ball, T. B. Cohorts for the study of HIV-1-exposed but uninfected individuals: Benefits and limitations. J. Infect. Dis. 202(Suppl 3), S377-381. https:// doi. org/ 10. 1086/ 655971 (2010).3. Fenizia, C., Saulle, I., Clerici, M. & Biasin, M. Genetic and epigenetic regulation of natural resistance to HIV-1 infection: New approaches to unveil the HESN secret. Expert Rev. Clin. Immunol. 16, 429–445. https:// doi. org/ 10. 1080/ 17446 66X. 2020. 17328 20 (2020).4. Fauci, A. S., Mavilio, D. & Kottilil, S. NK cells in HIV infection: Paradigm for protection or targets for ambush. Nat. Rev. Immunol. 5, 835–843. https:// doi. org/ 10. 1038/ nri17 11 (2005).5. Scott-Algara, D. et al. Cutting edge: Increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug users. J. Immunol. 171, 5663–5667. https:// doi. org/ 10. 4049/ jimmu nol. 171. 11. 5663 (2003).6. Tomescu, C., Abdulhaqq, S. & Montaner, L. J. Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN). Clin. Exp. Immunol. 164, 158–169. https:// doi. org/ 10. 1111/j. 1365- 2249. 2011. 04379.x (2011).7. Zhao, N. Q. et al. Natural killer cell phenotype is altered in HIV-exposed seronegative women. PLoS One 15, e0238347. https:// doi. org/ 10. 1371/ journ al. pone. 02383 47 (2020).8. Montoya, C. J., Velilla, P. A., Chougnet, C., Landay, A. L. & Rugeles, M. T. Increased IFN-gamma production by NK and CD3+/ CD56+ cells in sexually HIV-1-exposed but uninfected individuals. Clin. Immunol. 120, 138–146. https:// doi. org/ 10. 1016/j. clim. 2006. 02. 008 (2006).9. Florez-Alvarez, L. et al. NK cell activity and CD57(+)/NKG2C(high) phenotype are increased in men who have sex with men at high risk for HIV. Front. Immunol. 11, 537044. https:// doi. org/ 10. 3389/ fimmu. 2020. 537044 (2020).10. Mikulak, J., Oriolo, F., Zaghi, E., Di Vito, C. & Mavilio, D. Natural killer cells in HIV-1 infection and therapy. AIDS 31, 2317–2330. https:// doi. org/ 10. 1097/ qad. 00000 00000 001645 (2017).11. Pines, H. A., Karris, M. Y. & Little, S. J. Sexual partner concurrency among partners reported by MSM with recent HIV infection. AIDS Behav. 21, 3026–3034. https:// doi. org/ 10. 1007/ s10461- 017- 1855-x (2017).12. Tieu, H. V. et al. Concurrent partnerships and HIV risk among men who have sex with men in New York City. Sex Transm. Dis. 41, 200–208. https:// doi. org/ 10. 1097/ OLQ. 00000 00000 000090 (2014).13. Ossa-Giraldo, A. C. et al. Sexual behaviors and factors associated with condomless sexual practice in colombian men who have sex with men at high risk of HIV transmission. Arch. Sexual Behav. 50, 3175–3190. https:// doi. org/ 10. 1007/ s10508- 020- 01856-y (2021).14. Galvin, S. R. & Cohen, M. S. The role of sexually transmitted diseases in HIV transmission. Nat. Rev. Microbiol. 2, 33–42. https://doi. org/ 10. 1038/ nrmic ro794 (2004).15. Tobian, A. A. & Quinn, T. C. Herpes simplex virus type 2 and syphilis infections with HIV: An evolving synergy in transmission and prevention. Curr. Opin. HIV AIDS 4, 294–299. https:// doi. org/ 10. 1097/ COH. 0b013 e3283 2c1881 (2009).16. Bjorkstrom, N. K., Ljunggren, H. G. & Sandberg, J. K. CD56 negative NK cells: Origin, function, and role in chronic viral disease. Trends Immunol. 31, 401–406. https:// doi. org/ 10. 1016/j. it. 2010. 08. 003 (2010).17. Goodier, M. R. et al. Rapid NK cell differentiation in a population with near-universal human cytomegalovirus infection is attenuated by NKG2C deletions. Blood 124, 2213–2222. https:// doi. org/ 10. 1182/ blood- 2014- 05- 576124 (2014).18. Camous, X., Pera, A., Solana, R. & Larbi, A. NK cells in healthy aging and age-associated diseases. J. Biomed. Biotechnol. 2012, 195956. https:// doi. org/ 10. 1155/ 2012/ 195956 (2012).19. Richard, J., Sindhu, S., Pham, T. N., Belzile, J. P. & Cohen, E. A. HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing. Blood 115, 1354–1363. https:// doi. org/ 10. 1182/ blood- 2009- 08- 237370 (2010).20. Florez-Alvarez, L., Hernandez, J. C. & Zapata, W. NK cells in HIV-1 infection: From basic science to vaccine strategies. Front. 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