Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia
Introducción. La prevalencia del consumo de Cannabis sigue en aumento en el mundo, especialmente, entre adolescentes. Dicho consumo se sobrepone al de cigarrillos y otras sustancias lícitas e ilícitas, y se ha asociado con síntomas depresivos e incremento del riesgo suicida. En el contexto colombian...
- Autores:
-
Campo Arias, Adalberto
Caballero Dominguez, Carmen Cecilia
Suárez Colorado, Yuly Paola
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2020
- Institución:
- Universidad Cooperativa de Colombia
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- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/33209
- Palabra clave:
- Fumar marihuana
Suicidio
Adolescente
Estudiantes
Salud pública
Estudios transversales
Marijuana smoking
Suicide;
Adolescent
Students
Public health
Cross-sectional studies
- Rights
- closedAccess
- License
- Atribución – No comercial – Sin Derivar
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dc.title.spa.fl_str_mv |
Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia |
title |
Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia |
spellingShingle |
Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia Fumar marihuana Suicidio Adolescente Estudiantes Salud pública Estudios transversales Marijuana smoking Suicide; Adolescent Students Public health Cross-sectional studies |
title_short |
Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia |
title_full |
Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia |
title_fullStr |
Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia |
title_full_unstemmed |
Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia |
title_sort |
Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia |
dc.creator.fl_str_mv |
Campo Arias, Adalberto Caballero Dominguez, Carmen Cecilia Suárez Colorado, Yuly Paola |
dc.contributor.author.none.fl_str_mv |
Campo Arias, Adalberto Caballero Dominguez, Carmen Cecilia Suárez Colorado, Yuly Paola |
dc.subject.spa.fl_str_mv |
Fumar marihuana Suicidio Adolescente Estudiantes Salud pública Estudios transversales |
topic |
Fumar marihuana Suicidio Adolescente Estudiantes Salud pública Estudios transversales Marijuana smoking Suicide; Adolescent Students Public health Cross-sectional studies |
dc.subject.other.spa.fl_str_mv |
Marijuana smoking Suicide; Adolescent Students Public health Cross-sectional studies |
description |
Introducción. La prevalencia del consumo de Cannabis sigue en aumento en el mundo, especialmente, entre adolescentes. Dicho consumo se sobrepone al de cigarrillos y otras sustancias lícitas e ilícitas, y se ha asociado con síntomas depresivos e incremento del riesgo suicida. En el contexto colombiano poco se conoce sobre la relación entre el consumo de Cannabis y el riesgo de suicidio. Objetivo. Evaluar la asociación entre el consumo de Cannabis y el riesgo suicida en adolescentes escolarizados de Santa Marta, Colombia. Materiales y métodos. Se hizo un estudio transversal con una muestra probabilística de estudiantes de media vocacional entre los 13 y los 17 años de edad en colegios oficiales y privados. Se indagó sobre el consumo de Cannabis alguna vez en la vida y se cuantificó el riesgo suicida con la Center for Epidemiologic Studies on Depression Scale. Las puntuaciones superiores a ocho se categorizaron como riesgo suicida elevado. Se estimó la razón de oportunidad (OR) cruda y la ajustada. Resultados. Participaron 1.462 estudiantes. La media para la edad fue de 14,4 años (desviación estándar, DE=0,8) y el 60,3 % correspondía a mujeres. La prevalencia del consumo de Cannabis alguna vez en la vida fue del 11,6 % (IC95% 10,0-13,2) y el 13,3 % (IC95% 11,6-15,0) de los estudiantes presentó riesgo suicida elevado. El consumo de Cannabis se asoció con dicho riesgo ajustado por otras variables (OR=1,88; IC95% 1,23-2,88). Conclusiones. El consumo de Cannabis se asoció con el riesgo suicida elevado en adolescentes escolarizados de Santa Marta, Colombia. Es necesario analizar otras variables que pueden mediar esta asociación. |
publishDate |
2020 |
dc.date.issued.none.fl_str_mv |
2020-06 |
dc.date.accessioned.none.fl_str_mv |
2021-02-05T20:30:38Z |
dc.date.available.none.fl_str_mv |
2021-02-05T20:30:38Z |
dc.type.none.fl_str_mv |
Artículo |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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info:eu-repo/semantics/publishedVersion |
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dc.identifier.issn.spa.fl_str_mv |
2590-7379 |
dc.identifier.uri.spa.fl_str_mv |
https://doi.org/10.7705/biomedica.4988 |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12494/33209 |
dc.identifier.bibliographicCitation.spa.fl_str_mv |
Campo-Arias A, Suárez-Colorado YP, CaballeroDomínguez CC. Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia. Biomédica. 2020;40:569-77. https://doi.org/10.7705/biomedica.4988 |
identifier_str_mv |
2590-7379 Campo-Arias A, Suárez-Colorado YP, CaballeroDomínguez CC. Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia. Biomédica. 2020;40:569-77. https://doi.org/10.7705/biomedica.4988 |
url |
https://doi.org/10.7705/biomedica.4988 https://hdl.handle.net/20.500.12494/33209 |
dc.relation.isversionof.spa.fl_str_mv |
http://www.scielo.org.co/pdf/bio/v40n3/2590-7379-bio-40-03-569.pdf |
dc.relation.ispartofjournal.spa.fl_str_mv |
Revista Biomédia |
dc.relation.references.spa.fl_str_mv |
United National Office on Drugs and Crime. World Drug Report 2017. Vienna: United Nations; 2017 Martínez-Torres J, Rangel-Navia H, Rivera-Capacho E. Prevalencia de vida y factores asociados al consumo de marihuana en estudiantes escolarizados de Pamplona-Colombia, durante el primer período de 2015: estudio Emtamplona. Rev Med Chile. 2018;146:1016-23. https://doi.org/10.4067/s0034-98872018000901016 Guxensa M, Nebot M, Ariza C, Ochoa D. Factors associated with the onset of Cannabis use: A systematic review of cohort studies. Gac Sanit. 2007;21:252-60. https://doi.org/10.1157/13106811 Patton GC, Coffey C, Sawyer SM, Viner RM, Haller DM, Krishna Bose, et al. Global patterns of mortality in young people: A systematic analysis of population health data. Lancet. 2009;374:881-92. https://doi.org/10.1016/S0140-6736(09)60741-8 Ministerio de Salud. Encuesta Nacional de Salud Mental 2015. Bogotá: Minsalud; 2015. Hawton K, Saunders KEA, O’Connor RC. Self-harm and suicide in adolescents. Lancet. 2012;379:2373-82. https://doi.org/10.1016/S0140-6736(12)60322-5 Carvalho AF, Stubbs B, Vancampfort D, Kloiber S, Maes M, Firth J, et al. Cannabis use and suicide attempts among 86,254 adolescents aged 12-15 years from 21 low-and middleincome countries. Eur Psychiatry. 2019;56:8-13. https://doi.org/10.1016/j.eurpsy.2018.10.006 Chabrol H, Melioli T, Goutaudier N. Cannabis use and suicidal ideations in high-school students. Addict Behav. 2014;39:1766-8. https://doi.org/10.1016/j.addbeh.2014.06.008 Borges G, Bagge CL, Orozco R. A literature review and meta-analyses of Cannabis use and suicidality. J Affect Disord. 2016;195:63-74. https://doi.org/10.1016/j.jad.2016.02.007 Gobbi G, Atkin T, Zytynski T, Wang S, Askari S, Boruff J, et al. Association of Cannabis use in adolescence and risk of depression, anxiety, and suicidality in young adulthood: A systematic review and meta-analysis. JAMA Psychiatry. 2019;76:426-34. https://doi.org/10.1001/jamapsychiatry.2018.4500 Bridge JA, Goldstein TR, Brent DA. Adolescent suicide and suicidal behavior. J Child Psychol Psychiatry. 2006;47:372-94. https://doi.org/10.1111/j.1469-7610.2006.01615.x van Ours JC, Williams J. Cannabis use and mental health problems. J Appl Econometric. 2011;26:1137-56. https://doi.org/10.1002/jae.1182 McGee R, Williams S, Poulton R, Moffitt T. A longitudinal study of Cannabis use and mental health from adolescence to early adulthood. Addiction. 2000;95:491-503. https://doi.org/10.1046/j.1360-0443.2000.9544912.x van Ours JC, Williams J, Fergusson D, Horwood LJ. Cannabis use and suicidal ideation. J Health Econ. 2013;32:524-37. https://doi.org/10.1016/j.jhealeco.2013.02.002 van Ours JC, Williams J. The effects of Cannabis use on physical and mental health. J Health Econ. 2012;31:564-77. https://doi.org/10.1016/j.jhealeco.2012.04.003 Braakmann N, Jones S. Cannabis depenalisation, drug consumption and crime–Evidence from the 2004 Cannabis declassification in the UK. Soc Sci Med. 2014;115:29-37. https://doi.org/10.1016/j.socscimed.2014.06.003 Ministerio de Salud. Resolución 008430 por la cual se establecen las normas científicas, técnicas y administrativas para la investigación en salud. Bogotá, D. C.; Minsalud; 1993 Hernández J. Selección del tamaño de muestra en estudios clínicos. Rev Colomb Gastroenterol. 2006;21:118-21 Katz MH. Study design and statistical analysis. A practical guide for clinicians. Cambridge: Cambridge University Press; 2009. p.127-40. Kann L. Youth risk behavior surveillance—United States, 2015. MMWR Surveill Summ. 2016;65:1-174. https://doi.org/10.15585/mmwr.ss6506a1 Brener ND, Kann L, McManus T, Kinchen SA, Sundberg EC, Ross JG. Reliability of the 1999 youth risk behavior survey questionnaire. J Adolesc Health. 2002;31:336-42. https://doi.org/10.15585/mmwr.ss6506a1 Zullig KJ, Pun S, Patton JM, Ubbes VA. Reliability of the 2005 middle school youth risk behavior survey. J Adolesc Health. 2006;39:856-60. https://doi.org/10.1016/j.jadohealth.2006.07.008 Bae J, Joung H, Kim JY, Kwon KN, Kim YT, Park SW. Test-retest reliability of a questionnaire for the Korea Youth Risk Behavior Web-based Survey. J Prev Med Public Health. 2010;43:403-10. https://doi.org/10.3961/jpmph.2010.43.5.403 Campo-Arias A, Cogollo Z, Díaz CE. Comportamientos relacionados con la salud en adolescentes estudiantes: prevalencia y factores asociados. Salud Uninorte. 2008;24:226-34. Smilkstein G. The family APGAR: A proposal for a family function test and its uses by physicians. J Fam Pract. 1978;6:12-31. Forero LM, Avendaño MC, Duarte ZJ, Campo-Arias A. Consistencia interna y análisis de factores de la escala APGAR para evaluar el funcionamiento familiar en estudiantes de básica secundaria. Rev Colomb Psiquiatr. 2006;35:23-9. World Health Organization. Regional Office for Europe. Well-being measures in primary health care: The DepCare Project. Consensus meeting. Stockholm; WHO; 1998. Campo-Arias A, Miranda-Tapia GA, Cogollo Z, Herazo E. Reproducibilidad del Índice de Bienestar General (WHO-5 WBI) en adolescentes estudiantes. Salud Uninorte. 2015;31:18-24. Davidson JRT. Davidson Trauma Scale. North Tonawanda: The Multi-Health Systems Inc., 1996. Pineda DA, Guerrero OL, Pinilla ML, Estupiñán M. Utilidad de un cuestionario para rastreo del estrés postraumático en una población colombiana. Acta Neurol Colomb. 2002;18:132-8 Roberts R. Reliability of the CES-D Scale in different ethnic contexts. Psychiatry Res. 1980;2:125-34. https://doi.org/10.1016/0165-1781(80)90069-4 Pineda-Roa CA, Martínez-Chía, AP, Corredor-González DY, Herazo E, Campo-Arias A. Hallazgos psicométricos de la escala para ideación suicida del centro de estudios epidemiológicos en adolescentes escolarizados de Samacá, Boyacá, Colombia. Biosalud. 2018;17:47-55 Greenland S. Modeling and variable selection in epidemiologic analysis. Am J Public Health. 1989;79:340-9. https://doi.org/10.2105/ajph.79.3.340 Cronbach J. Coefficient alpha and the internal structure of test. Psychometrika. 1951;16:297-334 IBM-SPSS. Statistics for Windows, version 22.0. Armonk: SPSS. Inc.; 2013. Spremo M, Loga S. The relationship between suicidal thoughts and psychoactive substances. Bosn J Basic Med Sci. 2005;5:35-8. https://doi.org/10.17305/bjbms.2005.3268 Spears M, Montgomery AA, Gunnell D, Araya R. Factors associated with the development of self-harm amongst a socio-economically deprived cohort of adolescents in Santiago, Chile. Soc Psychiatry Psychiatr Epidemiol. 2014;49:629-37. https://doi.org/10.1007/s00127-013-0767-y Zarrouq B, Bendaou B, Elkinany S, Rammouz I, Aalouane R, Lyoussi B, et al. Suicidal behaviors among Moroccan school students: Prevalence and association with sociodemographic characteristics and psychoactive substances use: A cross-sectional study. BMC Psychiatry. 2015;15:284. https://doi.org/10.1186/s12888-015-0680-x Guvendeger N, Zahmacioglu O, Ciftci A, Kocaman GM, Erdogan A. Association of suicide attempts and non-suicidal self-injury behaviors with substance use and family characteristics among children and adolescents seeking treatment for substance use disorder. Subst Use Misuse. 2017;52:604-13. https://doi.org/10.1080/10826084.2016.1245745 Kleiman EM, Nock MK. Real-time assessment of suicidal thoughts and behaviors. Curr Opin Psychol. 2018;22:33-7. https://doi.org/10.1016/j.copsyc.2017.07.026 Hoch E, Bonnet U, Thomasius R, Ganzer F, Havemann-Reinecke U, Preuss UW. Risks associated with the non-medicinal use of Cannabis. Deutsch Ärzteblatt Int. 2015;112:271-8. https://doi.org/10.3238/arztebl.2015.0271 Clarke MC, Coughlan H, Harley M, Connor D, Power E, Lynch F, et al. The impact of adolescent Cannabis use, mood disorder and lack of education on attempted suicide in young adulthood. World Psychiatry. 2014;13:322-3. https://doi.org/10.1002/wps.20170 Silins E, Horwood LJ, Patton GC, Fergusson DM, Olsson CA, Hutchinson DM, et al. Young adult sequelae of adolescent Cannabis use: An integrative analysis. Lancet Psychiatry. 2014;1:286-93. https://doi.org/10.1016/S2215-0366(14)70307-4 Breet E, Goldstone D, Bantjes J. Substance use and suicidal ideation and behaviour in lowand middle-income countries: A systematic review. BMC Public Health. 2018;18:549. https://doi.org/10.1186/s12889-018-5425-6 Höfler M. The Bradford Hill considerations on causality: A counterfactual perspective. Emerging Themes Epidemiol. 2005,2:11. https://doi.org/10.1186/1742-7622-2-11 |
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9 |
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Vol 40 No 3 |
dc.publisher.spa.fl_str_mv |
Instituto Nacional de Salud Universidad Cooperativa de Colombia, Facultad de Ciencias Sociales, Programa de Psicología, Santa Marta, Colombia, |
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Psicología |
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Santa Marta |
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Universidad Cooperativa de Colombia |
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Campo Arias, AdalbertoCaballero Dominguez, Carmen CeciliaSuárez Colorado, Yuly Paola Vol 40 No 32021-02-05T20:30:38Z2021-02-05T20:30:38Z2020-062590-7379https://doi.org/10.7705/biomedica.4988https://hdl.handle.net/20.500.12494/33209Campo-Arias A, Suárez-Colorado YP, CaballeroDomínguez CC. Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia. Biomédica. 2020;40:569-77. https://doi.org/10.7705/biomedica.4988Introducción. La prevalencia del consumo de Cannabis sigue en aumento en el mundo, especialmente, entre adolescentes. Dicho consumo se sobrepone al de cigarrillos y otras sustancias lícitas e ilícitas, y se ha asociado con síntomas depresivos e incremento del riesgo suicida. En el contexto colombiano poco se conoce sobre la relación entre el consumo de Cannabis y el riesgo de suicidio. Objetivo. Evaluar la asociación entre el consumo de Cannabis y el riesgo suicida en adolescentes escolarizados de Santa Marta, Colombia. Materiales y métodos. Se hizo un estudio transversal con una muestra probabilística de estudiantes de media vocacional entre los 13 y los 17 años de edad en colegios oficiales y privados. Se indagó sobre el consumo de Cannabis alguna vez en la vida y se cuantificó el riesgo suicida con la Center for Epidemiologic Studies on Depression Scale. Las puntuaciones superiores a ocho se categorizaron como riesgo suicida elevado. Se estimó la razón de oportunidad (OR) cruda y la ajustada. Resultados. Participaron 1.462 estudiantes. La media para la edad fue de 14,4 años (desviación estándar, DE=0,8) y el 60,3 % correspondía a mujeres. La prevalencia del consumo de Cannabis alguna vez en la vida fue del 11,6 % (IC95% 10,0-13,2) y el 13,3 % (IC95% 11,6-15,0) de los estudiantes presentó riesgo suicida elevado. El consumo de Cannabis se asoció con dicho riesgo ajustado por otras variables (OR=1,88; IC95% 1,23-2,88). Conclusiones. El consumo de Cannabis se asoció con el riesgo suicida elevado en adolescentes escolarizados de Santa Marta, Colombia. Es necesario analizar otras variables que pueden mediar esta asociación.Introduction: The use of Cannabis continues to increase worldwide, especially among adolescents. This use overlaps with cigarette smoking and other illicit and licit drugs and is associated with depressive symptoms and suicide risk. In our national context, little is known about the relationship between Cannabis use and suicide risk. Objective: To evaluate the association between Cannabis use and elevated suicide risk in high school adolescents in Santa Marta, Colombia. Materials and methods: We conducted a cross-sectional study with a probabilistic sample of high school students between 13 and 17 years of age from official and private schools. We analyzed the use of Cannabis some time in life and suicide risk was quantified using the suicide ideation scale designed by the Center for Epidemiological Studies on Depression. Scores greater than eight were categorized as a high suicide risk. The crude and adjusted opportunity ratio (OR) was estimated. Results: A total of 1,462 students participated. Their mean age was 14.4 years (SD=0.8) and 60.3% were women. The lifetime prevalence of Cannabis use was 11.6% (95%CI: 10.013.2) and 13.3% of the students reported high suicide risk (95%CI: 11.6-15.0). Cannabis consumption was associated with high suicide risk adjusted by other variables (OR=1.88; 95%CI: 1.23-2.88). Conclusions: Cannabis use was associated with high suicide risk in high school adolescents in Santa Marta, Colombia. Other variables should be studied in order to further examine this association.https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001404153https://orcid.org/0000-0001-7715acampo@unimagdalena.edu.coccaballero@unimagdalena.edu.coyuli.suarezcol@campusucc.edu.cohttps://scholar.google.es/citations?user=mRUw4xIAAAAJ&hl=es&oi=ao9Instituto Nacional de SaludUniversidad Cooperativa de Colombia, Facultad de Ciencias Sociales, Programa de Psicología, Santa Marta, Colombia,PsicologíaSanta Martahttp://www.scielo.org.co/pdf/bio/v40n3/2590-7379-bio-40-03-569.pdfRevista BiomédiaUnited National Office on Drugs and Crime. World Drug Report 2017. Vienna: United Nations; 2017Martínez-Torres J, Rangel-Navia H, Rivera-Capacho E. Prevalencia de vida y factores asociados al consumo de marihuana en estudiantes escolarizados de Pamplona-Colombia, durante el primer período de 2015: estudio Emtamplona. Rev Med Chile. 2018;146:1016-23. https://doi.org/10.4067/s0034-98872018000901016Guxensa M, Nebot M, Ariza C, Ochoa D. Factors associated with the onset of Cannabis use: A systematic review of cohort studies. Gac Sanit. 2007;21:252-60. https://doi.org/10.1157/13106811Patton GC, Coffey C, Sawyer SM, Viner RM, Haller DM, Krishna Bose, et al. Global patterns of mortality in young people: A systematic analysis of population health data. Lancet. 2009;374:881-92. https://doi.org/10.1016/S0140-6736(09)60741-8Ministerio de Salud. Encuesta Nacional de Salud Mental 2015. Bogotá: Minsalud; 2015.Hawton K, Saunders KEA, O’Connor RC. Self-harm and suicide in adolescents. Lancet. 2012;379:2373-82. https://doi.org/10.1016/S0140-6736(12)60322-5Carvalho AF, Stubbs B, Vancampfort D, Kloiber S, Maes M, Firth J, et al. Cannabis use and suicide attempts among 86,254 adolescents aged 12-15 years from 21 low-and middleincome countries. Eur Psychiatry. 2019;56:8-13. https://doi.org/10.1016/j.eurpsy.2018.10.006Chabrol H, Melioli T, Goutaudier N. Cannabis use and suicidal ideations in high-school students. Addict Behav. 2014;39:1766-8. https://doi.org/10.1016/j.addbeh.2014.06.008Borges G, Bagge CL, Orozco R. A literature review and meta-analyses of Cannabis use and suicidality. J Affect Disord. 2016;195:63-74. https://doi.org/10.1016/j.jad.2016.02.007Gobbi G, Atkin T, Zytynski T, Wang S, Askari S, Boruff J, et al. Association of Cannabis use in adolescence and risk of depression, anxiety, and suicidality in young adulthood: A systematic review and meta-analysis. JAMA Psychiatry. 2019;76:426-34. https://doi.org/10.1001/jamapsychiatry.2018.4500Bridge JA, Goldstein TR, Brent DA. Adolescent suicide and suicidal behavior. J Child Psychol Psychiatry. 2006;47:372-94. https://doi.org/10.1111/j.1469-7610.2006.01615.xvan Ours JC, Williams J. Cannabis use and mental health problems. 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C.; Minsalud; 1993Hernández J. Selección del tamaño de muestra en estudios clínicos. Rev Colomb Gastroenterol. 2006;21:118-21Katz MH. Study design and statistical analysis. A practical guide for clinicians. Cambridge: Cambridge University Press; 2009. p.127-40.Kann L. Youth risk behavior surveillance—United States, 2015. MMWR Surveill Summ. 2016;65:1-174. https://doi.org/10.15585/mmwr.ss6506a1Brener ND, Kann L, McManus T, Kinchen SA, Sundberg EC, Ross JG. Reliability of the 1999 youth risk behavior survey questionnaire. J Adolesc Health. 2002;31:336-42. https://doi.org/10.15585/mmwr.ss6506a1Zullig KJ, Pun S, Patton JM, Ubbes VA. Reliability of the 2005 middle school youth risk behavior survey. J Adolesc Health. 2006;39:856-60. https://doi.org/10.1016/j.jadohealth.2006.07.008Bae J, Joung H, Kim JY, Kwon KN, Kim YT, Park SW. Test-retest reliability of a questionnaire for the Korea Youth Risk Behavior Web-based Survey. 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The relationship between suicidal thoughts and psychoactive substances. Bosn J Basic Med Sci. 2005;5:35-8. https://doi.org/10.17305/bjbms.2005.3268Spears M, Montgomery AA, Gunnell D, Araya R. Factors associated with the development of self-harm amongst a socio-economically deprived cohort of adolescents in Santiago, Chile. Soc Psychiatry Psychiatr Epidemiol. 2014;49:629-37. https://doi.org/10.1007/s00127-013-0767-yZarrouq B, Bendaou B, Elkinany S, Rammouz I, Aalouane R, Lyoussi B, et al. Suicidal behaviors among Moroccan school students: Prevalence and association with sociodemographic characteristics and psychoactive substances use: A cross-sectional study. BMC Psychiatry. 2015;15:284. https://doi.org/10.1186/s12888-015-0680-xGuvendeger N, Zahmacioglu O, Ciftci A, Kocaman GM, Erdogan A. Association of suicide attempts and non-suicidal self-injury behaviors with substance use and family characteristics among children and adolescents seeking treatment for substance use disorder. Subst Use Misuse. 2017;52:604-13. https://doi.org/10.1080/10826084.2016.1245745Kleiman EM, Nock MK. Real-time assessment of suicidal thoughts and behaviors. Curr Opin Psychol. 2018;22:33-7. https://doi.org/10.1016/j.copsyc.2017.07.026Hoch E, Bonnet U, Thomasius R, Ganzer F, Havemann-Reinecke U, Preuss UW. Risks associated with the non-medicinal use of Cannabis. Deutsch Ärzteblatt Int. 2015;112:271-8. https://doi.org/10.3238/arztebl.2015.0271Clarke MC, Coughlan H, Harley M, Connor D, Power E, Lynch F, et al. The impact of adolescent Cannabis use, mood disorder and lack of education on attempted suicide in young adulthood. World Psychiatry. 2014;13:322-3. https://doi.org/10.1002/wps.20170Silins E, Horwood LJ, Patton GC, Fergusson DM, Olsson CA, Hutchinson DM, et al. Young adult sequelae of adolescent Cannabis use: An integrative analysis. Lancet Psychiatry. 2014;1:286-93. https://doi.org/10.1016/S2215-0366(14)70307-4Breet E, Goldstone D, Bantjes J. Substance use and suicidal ideation and behaviour in lowand middle-income countries: A systematic review. BMC Public Health. 2018;18:549. https://doi.org/10.1186/s12889-018-5425-6Höfler M. The Bradford Hill considerations on causality: A counterfactual perspective. 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